Here is yet more scientific proof that overeating is not so good: you know how you feel drowsy and sort of dull after a really huge meal? Well, that's just your brain, like, shutting down.
From Science Daily
QUOTE In today's society, this pathway is mobilized by a different environmental challenge—overnutrition," he said. Once activated, "the pathway leads to a number of dysfunctions, including resistance to insulin and leptin," both important metabolic hormones. UNQUOTE